HCID 57092400, compound → HCID 66700088, compound

HRID 403680Notes

Reaction equation

HRID 403680 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([CH:9]=[C:10]([I:14])[C:11]=1[O:12][CH3:13])[NH2:8])([CH3:4])([CH3:3])[CH3:2].C([CH:17]([Cl:22])[CH2:18][N:19]=[C:20]=[O:21])C>>[C:1]([C:5]1[CH:6]=[C:7]([NH:8][C:20]([NH:19][CH2:18][CH2:17][Cl:22])=[O:21])[CH:9]=[C:10]([I:14])[C:11]=1[O:12][CH3:13])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 57092400HCID 57092400, compoundHCID 57419443HCID 57419443, compound

Product 1

HCID 66700088HCID 66700088, compound

Procedure

3-tert-Butyl-5-iodo-4-methoxyaniline (305 mg, 1 mmol) and ethyl 2-chloroethyl isocyanate (0.085 mL, 1.000 mmol) were reacted in the same manner as Example 15 Part A to give the title compound which was used without purification.

Sources & evidence

ORD record
ord-47e0cf6915fa49d3a7b152277f5d167b
Source dataset
uspto-grants-2014_06
Patent number
US08748443B2

Reaction notes

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