HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Methylphenyl isocyanate → (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-p-tolylureido)phenyl)isoindolin-2-yl)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Methylphenyl isocyanate | HCID 69325 | — |
| Reactant | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| Product | (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-p-tolylureido)phenyl)isoindolin-2-yl)butanoate | HCID 131731445 | — |
Reaction Steps
The compound of example 23 was prepared analogous to compound of example 7 by reaction of compound of example 6 with 4-methyl phenyl isocyanate. The compound of example 23 was used directly without isolation for the preparation of compound of example 24.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-7d68082ce236427abec83fc331671aa5 |
| Source note | uspto-grants-2014_06 |