HRID403732

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID2734896

4-Phenoxyphenyl isocyanate

C13H9NO2

结构：COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(N)cc3)cc2C1=O

HCID131731441

未命名化合物

PRODUCTS

生成物

结构：COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NC(=O)Nc4ccc(Oc5ccccc5)cc4)cc3)cc2C1=O

HCID123570995

未命名化合物

收率 98%

PROCEDURE

实验过程

The compound of example 49 was prepared analogous to compound of example 7 by reaction of compound of example 6 with 4-phenoxy phenyl isocyanate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4d0c9c8a7c6a4f298b99217347d4c45e
来源数据集: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08748426B2
来源说明: uspto-grants-2014_06

反应 SMILES

[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:16]=[C:15]3[C:11]([CH2:12][N:13]([C@@H:18]([CH:23]([CH3:25])[CH3:24])[C:19]([O:21][CH3:22])=[O:20])[C:14]3=[O:17])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[O:26]([C:33]1[CH:38]=[CH:37][C:36]([N:39]=[C:40]=[O:41])=[CH:35][CH:34]=1)[C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>>[CH3:24][CH:23]([CH3:25])[C@H:18]([N:13]1[CH2:12][C:11]2[C:15](=[CH:16][C:8]([C:5]3[CH:4]=[CH:3][C:2]([NH:1][C:40]([NH:39][C:36]4[CH:37]=[CH:38][C:33]([O:26][C:27]5[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=5)=[CH:34][CH:35]=4)=[O:41])=[CH:7][CH:6]=3)=[CH:9][CH:10]=2)[C:14]1=[O:17])[C:19]([O:21][CH3:22])=[O:20]