HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-p-tolylthioureido)phenyl)isoindolin-2-yl)butanoate → (S)-3-Methyl-2-(1-oxo-6-(4-(3-p-tolylthioureido)phenyl)isoindolin-2-yl)butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-p-tolylthioureido)phenyl)isoindolin-2-yl)butanoate | HCID 53303392 | — |
| Reactant | (S)-2-(6-(4-(3-(2-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 87349957 | — |
| Product | (S)-3-Methyl-2-(1-oxo-6-(4-(3-p-tolylthioureido)phenyl)isoindolin-2-yl)butanoic acid | HCID 87349995 | 83% |
Reaction Steps
The compound of example 54 was prepared analogous to compound of example 52 by hydrolysis of compound of example 53.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-aaa5c5fee40e41e183294b4d071bf845 |
| Source note | uspto-grants-2014_06 |