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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403739Generated: October 25, 2026

(S)-2-(6-(4-(3-(2-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-2-(6-(4-(3-(3-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid

https://huagongshe.com/reaction/403739

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(6-(4-(3-(2-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acidHCID 87349957—
Reactant(S)-Methyl 2-(6-(4-(3-(3-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731451—
Product(S)-2-(6-(4-(3-(3-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acidHCID 8734999693%

Reaction Steps

The compound of example 56 was prepared analogous to compound of example 52 by hydrolysis of compound of example 55.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-6a8d7664f0544072a0e58294c3ce0a18
Source noteuspto-grants-2014_06