HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylphenyl isothiocyanate → HCID 131731457, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylphenyl isothiocyanate | HCID 69195 | — |
| Reactant | (S)-Methyl 2-(6-(4-(3-(2-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 53303391 | — |
| Reactant | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| Product | HCID 131731457 | HCID 131731457 | — |
Reaction Steps
The compound of example 71 was prepared analogous to compound of example 51 by reaction of compound of example 6 with 2-methyl phenyl isothiocyanate. The compound of example 71 was used directly without isolation for the preparation of compound of example 72.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-01d28358bc3649e7a18e3800ec5f154d |
| Source note | uspto-grants-2014_06 |