HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → HCID 53303514, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Benzenesulfonyl chloride | HCID 7369 | — |
| Reactant | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 53303514 | HCID 53303514 | — |
Reaction Steps
To a solution of compound of example 6 (0.250 g, 0.0073 mol) in dichloromethane (5 mL), pyridine (0.174 g, 0.00219 mol) was added and stirred for 5 min. To this reaction mixture, benzene sulfonyl chloride was added and stirred for about 16 h. After completion of the reaction, solvent was evaporated and the crude title compound obtained was directly used for the preparation of compound of example 78.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-e6ac56550a9a444aba092b54ea55dc4d |
| Source note | uspto-grants-2014_06 |