(S)-3-Methyl-2-(1-oxo-6-(4-(phenylsulfonamido)phenyl)isoindolin-2-yl)butanoic acid → (S)-2-(6-(4-(4-Cyanophenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid

Participants

Role	Name	HCID	Charge
Reactant	(S)-3-Methyl-2-(1-oxo-6-(4-(phenylsulfonamido)phenyl)isoindolin-2-yl)butanoic acid	HCID 67306729	—
Reactant	(S)-Methyl 2-(6-(4-(4-cyanophenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate	HCID 131731459	—
Product	(S)-2-(6-(4-(4-Cyanophenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid	HCID 53303516	93%

The compound of example 80 was prepared analogous to compound of example 78 by hydrolysis of compound of example 79.