3,4-Difluorobenzene-1-sulfonyl chloride → (S)-Methyl 2-(6-(4-(3,4-difluorophenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate

Participants

Reaction Steps

The compound of example 81 was prepared analogous to compound of example 77 by reaction of compound of example 6 with 3,4-difluorobenzene sulfonyl chloride. The compound of example 81 was used directly without isolation for the preparation of compound of example 82.

Provenance & Evidence