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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403761Generated: October 30, 2026

(S)-3-Methyl-2-(1-oxo-6-(4-(phenylsulfonamido)phenyl)isoindolin-2-yl)butanoic acid → (S)-2-(6-(4-(3,4-Dimethoxyphenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid

https://huagongshe.com/reaction/403761

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-3-Methyl-2-(1-oxo-6-(4-(phenylsulfonamido)phenyl)isoindolin-2-yl)butanoic acidHCID 67306729—
Reactant(S)-Methyl 2-(6-(4-(3,4-dimethoxyphenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731461—
Product(S)-2-(6-(4-(3,4-Dimethoxyphenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acidHCID 6730724289%

Reaction Steps

The compound of example 86 was prepared analogous to compound of example 78 by hydrolysis of compound of example 85.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-d512c62c1bcb44b8badb946fbd7113ef
Source noteuspto-grants-2014_06