HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-3-Methyl-2-(1-oxo-6-(4-(phenylsulfonamido)phenyl)isoindolin-2-yl)butanoic acid → (S)-2-(6-(4-(3-Chlorophenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-3-Methyl-2-(1-oxo-6-(4-(phenylsulfonamido)phenyl)isoindolin-2-yl)butanoic acid | HCID 67306729 | — |
| Reactant | (S)-Methyl 2-(6-(4-(3-chlorophenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731462 | — |
| Product | (S)-2-(6-(4-(3-Chlorophenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 67307490 | 89% |
Reaction Steps
The compound of example 88 was prepared analogous to compound of example 78 by hydrolysis of compound of example 87.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-ed40ad7603b04fdf85ce2b09e7d4d4b4 |
| Source note | uspto-grants-2014_06 |