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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403764Generated: October 29, 2026

4-Methoxybenzenesulfonyl chloride → (S)-Methyl 2-(6-(4-(4-methoxyphenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate

https://huagongshe.com/reaction/403764

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Methoxybenzenesulfonyl chlorideHCID 7401—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
Product(S)-Methyl 2-(6-(4-(4-methoxyphenylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731463—

Reaction Steps

The compound of example 89 was prepared analogous to compound of example 77 by reaction of compound of example 6 with 4-methoxybenzene sulfonyl chloride. The compound of example 89 was used directly without isolation for the preparation of compound of example 90.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-9a167952a92c4bad97bb2e0ab0ca68db
Source noteuspto-grants-2014_06