HRID403767

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COC(=O)[C@H](C(C)C)N1Cc2ccc(-c3ccc(NS(=O)(=O)c4ccc(C(F)(F)F)cc4)cc3)cc2C1=O

HCID53303515

未命名化合物

结构：CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NS(=O)(=O)c4ccccc4)cc3)cc2C1=O

HCID67306729

未命名化合物

PRODUCTS

生成物

结构：CC(C)[C@@H](C(=O)O)N1Cc2ccc(-c3ccc(NS(=O)(=O)c4ccc(C(F)(F)F)cc4)cc3)cc2C1=O

HCID67308110

未命名化合物

收率 93%

PROCEDURE

实验过程

The compound of example 92 was prepared analogous to compound of example 78 by hydrolysis of compound of example 91.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4e77a5cadbe840ce820e3fb7c71f7d2b
来源数据集: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08748426B2
来源说明: uspto-grants-2014_06

反应 SMILES

CC(C)[C@H](N1CC2C(=CC(C3C=CC(NS(C4C=CC=CC=4)(=O)=O)=CC=3)=CC=2)C1=O)C(O)=O.[CH3:34][CH:35]([CH3:71])[C@H:36]([N:41]1[CH2:49][C:48]2[C:43](=[CH:44][C:45]([C:50]3[CH:55]=[CH:54][C:53]([NH:56][S:57]([C:60]4[CH:65]=[CH:64][C:63]([C:66]([F:69])([F:68])[F:67])=[CH:62][CH:61]=4)(=[O:59])=[O:58])=[CH:52][CH:51]=3)=[CH:46][CH:47]=2)[C:42]1=[O:70])[C:37]([O:39]C)=[O:38]>>[CH3:34][CH:35]([CH3:71])[C@H:36]([N:41]1[CH2:49][C:48]2[C:43](=[CH:44][C:45]([C:50]3[CH:51]=[CH:52][C:53]([NH:56][S:57]([C:60]4[CH:65]=[CH:64][C:63]([C:66]([F:69])([F:68])[F:67])=[CH:62][CH:61]=4)(=[O:59])=[O:58])=[CH:54][CH:55]=3)=[CH:46][CH:47]=2)[C:42]1=[O:70])[C:37]([OH:39])=[O:38]