HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylmethanesulfonyl chloride → (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(phenylmethylsulfonamido)phenyl)isoindolin-2-yl)butanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylmethanesulfonyl chloride | HCID 74740 | — |
| Reactant | (S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731441 | — |
| Product | (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(phenylmethylsulfonamido)phenyl)isoindolin-2-yl)butanoate | HCID 131731464 | — |
Reaction Steps
The compound of example 93 was prepared analogous to compound of example 77 by reaction of compound of example 6 with benzyl sulfonyl chloride. The compound of example 93 was used directly without isolation for the preparation of compound of example 94.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-109baa65a59d4d9a86854728922ef327 |
| Source note | uspto-grants-2014_06 |