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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403770Generated: October 30, 2026

2-Propanesulfonyl chloride → (S)-Methyl 3-methyl-2-(6-(4-(1-methylethylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)butanoate

https://huagongshe.com/reaction/403770

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Propanesulfonyl chlorideHCID 82408—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
Product(S)-Methyl 3-methyl-2-(6-(4-(1-methylethylsulfonamido)phenyl)-1-oxoisoindolin-2-yl)butanoateHCID 131731465—

Reaction Steps

The compound of example 95 was prepared analogous to compound of example 77 by reaction of compound of example 6 with isopropyl sulfonyl chloride. The compound of example 95 was used directly without isolation for the preparation of compound of example 96.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-80c7a8b97d7149ff81b7cdfb928d60b4
Source noteuspto-grants-2014_06