Oxolan-3-yl methanesulfonate → 4-bromo-1-(oxolan-3-yl)-1H-pyrazole

HRID 40378Notes

Reaction equation

HRID 40378 reaction equation
[Br:1][C:2]1[CH:3]=[N:4][N:5]([CH:7]2[CH2:10][CH2:9][CH2:8]2)[CH:6]=1.CS(OC1CCOC1)(=O)=[O:13]>>[Br:1][C:2]1[CH:3]=[N:4][N:5]([CH:7]2[CH2:10][CH2:9][O:13][CH2:8]2)[CH:6]=1

Participants

3

Reactant 2

HCID 15278452Oxolan-3-yl methanesulfonateHCID 665214554-BroMo-1-cyclobutylpyrazole

Product 1

HCID 592316834-bromo-1-(oxolan-3-yl)-1H-pyrazole

Procedure

The title compound was prepared in the same manner as 4-bromo-1-(cyclobutyl)-1H-pyrazole, but using tetrahydrofuran-3-yl methanesulfonate (prepared according to procedures known in the art).

Workup

  1. customprepared

Sources & evidence

ORD record
ord-015c95e94c6048b081c3b3e69fedc934
Source dataset
uspto-grants-2013_09
Patent number
US08524900B2

Reaction notes

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