HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-2-(6-(4-(2,4-Difluorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 53303631 | — |
| Reactant | (S)-Methyl 2-(6-(4-(2,4-difluorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 53303632 | — |
| Product | (S)-2-(6-(4-(2,4-Difluorobenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid | HCID 67307333 | 84% |
Reaction Steps
The compound of example 110 was prepared analogous to compound of example 98 by hydrolysis of compound of example 109.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-f02995a136a940e3b1693779df810f9a |
| Source note | uspto-grants-2014_06 |