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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403809Generated: October 26, 2026

3-Phenoxybenzoyl chloride → (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-phenoxybenzamido)phenyl)isoindolin-2-yl)butanoate

https://huagongshe.com/reaction/403809

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Phenoxybenzoyl chlorideHCID 2760341—
Reactant(S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123625862—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
Product(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-phenoxybenzamido)phenyl)isoindolin-2-yl)butanoateHCID 5330374370%

Reaction Steps

The compound of example 147 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 3-phenoxy benzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-f7f7c25459154eedb9d0a929bd1fc505
Source noteuspto-grants-2014_06