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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403810Generated: October 30, 2026

(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-3-Methyl-2-(1-oxo-6-(4-(3-phenoxybenzamido)phenyl)isoindolin-2-yl)butanoic acid

https://huagongshe.com/reaction/403810

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acidHCID 53303631—
Reactant(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(3-phenoxybenzamido)phenyl)isoindolin-2-yl)butanoateHCID 53303743—
Product(S)-3-Methyl-2-(1-oxo-6-(4-(3-phenoxybenzamido)phenyl)isoindolin-2-yl)butanoic acidHCID 7097532083.44%

Reaction Steps

The compound of example 148 was prepared analogous to compound of example 98 by hydrolysis of compound of example 147.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-93cf9ed6f55840258d38ef53b8f3e92d
Source noteuspto-grants-2014_06