HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-2-(6-(4-(4-Fluoro-3-methylbenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 53303631 | — |
| Reactant | (S)-Methyl 2-(6-(4-(4-fluoro-3-methylbenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731483 | — |
| Product | (S)-2-(6-(4-(4-Fluoro-3-methylbenzamido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid | HCID 53303744 | 85% |
Reaction Steps
The compound of example 162 was prepared analogous to compound of example 98 by hydrolysis of compound of example 161.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-3ac6a94e20fc4997a4b605c99cf7c0dd |
| Source note | uspto-grants-2014_06 |