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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403827Generated: October 25, 2026

4-Propylbenzoyl chloride → (S)-Methyl 3-methyl-2-(1-oxo-6-(4-(4-propylbenzamido)phenyl)isoindolin-2-yl)butanoate

https://huagongshe.com/reaction/403827

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Propylbenzoyl chlorideHCID 104293—
Reactant(S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123625862—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
Product(S)-Methyl 3-methyl-2-(1-oxo-6-(4-(4-propylbenzamido)phenyl)isoindolin-2-yl)butanoateHCID 13173148591%

Reaction Steps

The compound of example 169 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 4-(n-propyl)benzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-083a7b1d5e9a4b538d401ebcabf8eb27
Source noteuspto-grants-2014_06