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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403829Generated: October 27, 2026

Benzoyl chloride, 4-octyl- → (S)-Methyl 3-methyl-2-(6-(4-(4-octylbenzamido)phenyl)-1-oxoisoindolin-2-yl)butanoate

https://huagongshe.com/reaction/403829

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzoyl chloride, 4-octyl-HCID 170865—
Reactant(S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 123625862—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
Product(S)-Methyl 3-methyl-2-(6-(4-(4-octylbenzamido)phenyl)-1-oxoisoindolin-2-yl)butanoateHCID 13173148698%

Reaction Steps

The compound of example 171 was prepared analogous to compound of example 97 by reaction of compound of example 6 with 4-(n-octyl)benzoyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-7673c26eed0e44b2ab6987d30006963c
Source noteuspto-grants-2014_06