HCID 53303947, compound → HCID 67307187, compound

HRID 403856Notes

Reaction equation

HRID 403856 reaction equation
[CH3:1][CH:2]([CH3:38])[C@H:3]([N:7]1[CH2:15][C:14]2[C:9](=[CH:10][C:11]([C:16]3[CH:21]=[CH:20][C:19]([NH:22][C:23](=[O:36])[C:24]4[CH:29]=[CH:28][C:27]([N:30]5[CH2:35][CH2:34]O[CH2:32][CH2:31]5)=[N:26][CH:25]=4)=[CH:18][CH:17]=3)=[CH:12][CH:13]=2)[C:8]1=[O:37])[C:4]([OH:6])=[O:5].CC(C)[C@H](N1CC2C(=CC(C3C=CC(NC(=O)C4C=CC(N5CCCC5)=NC=4)=CC=3)=CC=2)C1=O)C(OC)=O>>[CH3:38][CH:2]([CH3:1])[C@H:3]([N:7]1[CH2:15][C:14]2[C:9](=[CH:10][C:11]([C:16]3[CH:17]=[CH:18][C:19]([NH:22][C:23](=[O:36])[C:24]4[CH:29]=[CH:28][C:27]([N:30]5[CH2:31][CH2:32][CH2:34][CH2:35]5)=[N:26][CH:25]=4)=[CH:20][CH:21]=3)=[CH:12][CH:13]=2)[C:8]1=[O:37])[C:4]([OH:6])=[O:5]

Participants

3

Reactant 2

HCID 53303947HCID 53303947, compoundHCID 67306838HCID 67306838, compound

Product 1

HCID 67307187HCID 67307187, compoundYield 67%

Procedure

The compound of example 217 was prepared analogous to compound of example 213 by hydrolysis of compound of example 216.

Sources & evidence

ORD record
ord-0e3b9b062c7d43ef843fe38b2bb9c936
Source dataset
uspto-grants-2014_06
Patent number
US08748426B2

Reaction notes

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