HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(5-(4-(3-(4-Fluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-2-(5-(4-(3-(4-Methoxyphenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(5-(4-(3-(4-Fluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 67306564 | — |
| Reactant | (S)-Methyl 2-(5-(4-(3-(4-methoxyphenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731505 | — |
| Product | (S)-2-(5-(4-(3-(4-Methoxyphenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 67307426 | 95% |
Reaction Steps
The compound of example 249 was prepared analogous to compound of example 225 by hydrolysis of compound of example 248.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-3bc7b594eff44a7cb198f92b8e90235d |
| Source note | uspto-grants-2014_06 |