HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyanophenyl isocyanate → HCID 131731507, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyanophenyl isocyanate | HCID 170380 | — |
| Reactant | (S)-Methyl 2-(5-(4-(3-(4-fluorophenyl)ureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 123620640 | — |
| Reactant | (S)-Methyl 2-(5-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731499 | — |
| Product | HCID 131731507 | HCID 131731507 | — |
Reaction Steps
The compound of example 252 was prepared analogous to compound of example 224 by reaction of compound of example 223 with 4-cyanophenyl isocyanate. The compound of example 252 was used directly without isolation for the preparation of compound of example 253.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-7a9b841c7875429a9e25282b2568c154 |
| Source note | uspto-grants-2014_06 |