Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403902Generated: October 30, 2026

(S)-2-(5-(4-(3-(2-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → (S)-2-(5-(4-(3-(3-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid

https://huagongshe.com/reaction/403902

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(5-(4-(3-(2-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acidHCID 87349473—
Reactant(S)-Methyl 2-(5-(4-(3-(3-fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731510—
Product(S)-2-(5-(4-(3-(3-Fluorophenyl)thioureido)phenyl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acidHCID 8734991760%

Reaction Steps

The compound of example 277 was prepared analogous to compound of example 257 by hydrolysis of compound of example 276.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-2488e327255b46e799274f99429aa16e
Source noteuspto-grants-2014_06