HCID 67307075, compound → HCID 67307576, compound

HRID 403921Notes

Reaction equation

HRID 403921 reaction equation
C(NC1C=CC(C2C=C3C(=CC=2)C(=O)N([C@@H](C(C)C)C(O)=O)C3)=CC=1)(=O)C1C=CC=CC=1.[CH3:33][O:34][C:35]1[CH:67]=[CH:66][C:38]([C:39]([NH:41][C:42]2[CH:47]=[CH:46][C:45]([C:48]3[CH:49]=[C:50]4[C:54](=[CH:55][CH:56]=3)[C:53](=[O:57])[N:52]([C@@H:58]([CH:63]([CH3:65])[CH3:64])[C:59]([O:61]C)=[O:60])[CH2:51]4)=[CH:44][CH:43]=2)=[O:40])=[CH:37][CH:36]=1>>[CH3:33][O:34][C:35]1[CH:36]=[CH:37][C:38]([C:39]([NH:41][C:42]2[CH:43]=[CH:44][C:45]([C:48]3[CH:49]=[C:50]4[C:54](=[CH:55][CH:56]=3)[C:53](=[O:57])[N:52]([C@@H:58]([CH:63]([CH3:64])[CH3:65])[C:59]([OH:61])=[O:60])[CH2:51]4)=[CH:46][CH:47]=2)=[O:40])=[CH:66][CH:67]=1

Participants

3

Reactant 2

HCID 67307075HCID 67307075, compoundHCID 131731526HCID 131731526, compound

Product 1

HCID 67307576HCID 67307576, compoundYield 79%

Procedure

The compound of example 311 was prepared analogous to compound of example 305 by hydrolysis of compound of example 310.

Sources & evidence

ORD record
ord-bd709c33f3664cd491def9c2e005aa64
Source dataset
uspto-grants-2014_06
Patent number
US08748426B2

Reaction notes

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