HCID 67307075, compound → HCID 67307458, compound

HRID 403925Notes

Reaction equation

HRID 403925 reaction equation
C(NC1C=CC(C2C=C3C(=CC=2)C(=O)N([C@@H](C(C)C)C(O)=O)C3)=CC=1)(=O)C1C=CC=CC=1.[CH3:33][CH:34]([CH3:66])[C@H:35]([N:40]1[CH2:48][C:47]2[C:42](=[CH:43][CH:44]=[C:45]([C:49]3[CH:54]=[CH:53][C:52]([NH:55][C:56](=[O:64])[C:57]4[CH:62]=[CH:61][C:60]([CH3:63])=[CH:59][CH:58]=4)=[CH:51][CH:50]=3)[CH:46]=2)[C:41]1=[O:65])[C:36]([O:38]C)=[O:37]>>[CH3:33][CH:34]([CH3:66])[C@H:35]([N:40]1[CH2:48][C:47]2[C:42](=[CH:43][CH:44]=[C:45]([C:49]3[CH:54]=[CH:53][C:52]([NH:55][C:56](=[O:64])[C:57]4[CH:58]=[CH:59][C:60]([CH3:63])=[CH:61][CH:62]=4)=[CH:51][CH:50]=3)[CH:46]=2)[C:41]1=[O:65])[C:36]([OH:38])=[O:37]

Participants

3

Reactant 2

HCID 67307075HCID 67307075, compoundHCID 131731528HCID 131731528, compound

Product 1

HCID 67307458HCID 67307458, compoundYield 93%

Procedure

The compound of example 319 was prepared analogous to compound of example 305 by hydrolysis of compound of example 318.

Sources & evidence

ORD record
ord-2e11461c9f9c43dcbe8ceff68d2f2049
Source dataset
uspto-grants-2014_06
Patent number
US08748426B2

Reaction notes

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