HCID 67307075, compound → HCID 67308448, compound

HRID 403927Notes

Reaction equation

HRID 403927 reaction equation
C(NC1C=CC(C2C=C3C(=CC=2)C(=O)N([C@@H](C(C)C)C(O)=O)C3)=CC=1)(=O)C1C=CC=CC=1.[C:33]([C:37]1[CH:69]=[CH:68][C:40]([C:41]([NH:43][C:44]2[CH:49]=[CH:48][C:47]([C:50]3[CH:51]=[C:52]4[C:56](=[CH:57][CH:58]=3)[C:55](=[O:59])[N:54]([C@@H:60]([CH:65]([CH3:67])[CH3:66])[C:61]([O:63]C)=[O:62])[CH2:53]4)=[CH:46][CH:45]=2)=[O:42])=[CH:39][CH:38]=1)([CH3:36])([CH3:35])[CH3:34]>>[C:33]([C:37]1[CH:69]=[CH:68][C:40]([C:41]([NH:43][C:44]2[CH:45]=[CH:46][C:47]([C:50]3[CH:51]=[C:52]4[C:56](=[CH:57][CH:58]=3)[C:55](=[O:59])[N:54]([C@@H:60]([CH:65]([CH3:66])[CH3:67])[C:61]([OH:63])=[O:62])[CH2:53]4)=[CH:48][CH:49]=2)=[O:42])=[CH:39][CH:38]=1)([CH3:35])([CH3:34])[CH3:36]

Participants

3

Reactant 2

HCID 67307075HCID 67307075, compoundHCID 131731529HCID 131731529, compound

Product 1

HCID 67308448HCID 67308448, compoundYield 76%

Procedure

The compound of example 323 was prepared analogous to compound of example 305 by hydrolysis of compound of example 322.

Sources & evidence

ORD record
ord-3fbf78cda07441da9218b12d5396d36e
Source dataset
uspto-grants-2014_06
Patent number
US08748426B2

Reaction notes

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