HCID 53302439, compound → HCID 67305639, compound

HRID 403929Notes

Reaction equation

HRID 403929 reaction equation
C(NC1C=CC(C2C=C3C(=CC=2)C(=O)N([C@@H](C(C)C)C(O)=O)C3)=CC=1)(=O)C1C=CC=CC=1.[CH3:33][CH:34]([CH3:70])[C@H:35]([N:40]1[CH2:48][C:47]2[C:42](=[CH:43][CH:44]=[C:45]([C:49]3[CH:54]=[CH:53][C:52]([NH:55][C:56](=[O:68])[C:57]4[CH:62]=[CH:61][C:60]([CH2:63][CH2:64][CH2:65][CH2:66][CH3:67])=[CH:59][CH:58]=4)=[CH:51][CH:50]=3)[CH:46]=2)[C:41]1=[O:69])[C:36]([O:38]C)=[O:37]>>[CH3:70][CH:34]([CH3:33])[C@H:35]([N:40]1[CH2:48][C:47]2[C:42](=[CH:43][CH:44]=[C:45]([C:49]3[CH:54]=[CH:53][C:52]([NH:55][C:56](=[O:68])[C:57]4[CH:58]=[CH:59][C:60]([CH2:63][CH2:64][CH2:65][CH2:66][CH3:67])=[CH:61][CH:62]=4)=[CH:51][CH:50]=3)[CH:46]=2)[C:41]1=[O:69])[C:36]([OH:38])=[O:37]

Participants

3

Reactant 2

HCID 53302439HCID 53302439, compoundHCID 67307075HCID 67307075, compound

Product 1

HCID 67305639HCID 67305639, compoundYield 71.7%

Procedure

The compound of example 325 was prepared analogous to compound of example 305 by hydrolysis of compound of example 324.

Sources & evidence

ORD record
ord-dad2845775964283bb601c6989aad53b
Source dataset
uspto-grants-2014_06
Patent number
US08748426B2

Reaction notes

Loading…