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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403933Generated: October 30, 2026

Glycine methyl ester hydrochloride → Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)acetate

https://huagongshe.com/reaction/403933

Reaction equation

Participants

RoleNameHCIDCharge
ReactantGlycine methyl ester hydrochlorideHCID 122755—
Reactant(R)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731530—
ProductMethyl 2-(6-bromo-1-oxoisoindolin-2-yl)acetateHCID 67307273—

Reaction Steps

The compound of example 332 was prepared analogous to compound of example 329 by reaction of the compound of example 328 and glycine methyl ester hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-a98d817003a24bafaabbcf5931cf6cca
Source noteuspto-grants-2014_06