HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-Methyl-2-(1-oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)iso indolin-2-yl)butanoic acid → 2-(1-Oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-Methyl-2-(1-oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)iso indolin-2-yl)butanoic acid | HCID 67306771 | — |
| Reactant | Methyl 2-(1-oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)acetate | HCID 67307468 | — |
| Product | 2-(1-Oxo-6-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)acetic acid | HCID 53304159 | 91% |
Reaction Steps
The compound of example 334 was prepared analogous to compound of example 331 by hydrolysis of the compound of example 333.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-ae116bccc2a744bc80810f44a09fe447 |
| Source note | uspto-grants-2014_06 |