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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403936Generated: October 30, 2026

Alanine methyl ester hydrochloride → (S)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)propanoate

https://huagongshe.com/reaction/403936

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAlanine methyl ester hydrochlorideHCID 2733257—
Reactant(R)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731530—
Product(S)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)propanoateHCID 125486231—

Reaction Steps

The compound of example 335 was prepared analogous to compound of example 329 by reaction of the compound of example 328 and L-alanine methyl ester hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-b0490ab00d83423f8000ab11a76cf2d4
Source noteuspto-grants-2014_06