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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403947Generated: October 25, 2026

4-Aminobutyric acid methyl ester hydrochloride → Methyl 4-(6-bromo-1-oxoisoindolin-2-yl)butanoate

https://huagongshe.com/reaction/403947

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Aminobutyric acid methyl ester hydrochlorideHCID 2756383—
Reactant(R)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731530—
ProductMethyl 4-(6-bromo-1-oxoisoindolin-2-yl)butanoateHCID 67307579—

Reaction Steps

The compound of example 347 was prepared analogous to compound of example 329 by reaction of the compound of example 328 and methyl 4-aminobutanoate hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-226e535caab547fd9b5996ad4057e6b2
Source noteuspto-grants-2014_06