HuagongsheHuagongshe Chemistry Print Report · For research reference only
Valine, methyl ester, hydrochloride (1:1) → (S)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-3-methoxypropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Valine, methyl ester, hydrochloride (1:1) | HCID 12498813 | — |
| Reactant | (R)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 131731530 | — |
| Product | (S)-Methyl 2-(6-bromo-1-oxoisoindolin-2-yl)-3-methoxypropanoate | HCID 131731534 | 65% |
Reaction Steps
The compound of example 353 was prepared analogous to compound of example 329 by reaction of the compound of example 328 and methyl 2-amino-3-methylbutanoate hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-580af22a1a444c08ac6264d13d947d84 |
| Source note | uspto-grants-2014_06 |