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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403959Generated: October 26, 2026

Methyl 2-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)acetate → 2-(1-Oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)acetic acid

https://huagongshe.com/reaction/403959

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 2-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)acetateHCID 53302441—
Reactant(R)-3-Methyl-2-(1-oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)butanoic acidHCID 67308300—
Product2-(1-Oxo-5-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)isoindolin-2-yl)acetic acidHCID 67308049—

Reaction Steps

The compound of example 364 was prepared analogous to the compound of example 361 by hydrolysis of the compound of example 363.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-5e67916d53464f31865a2438abe35ca7
Source noteuspto-grants-2014_06