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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403963Generated: October 25, 2026

Methyl 1-amino-1-cyclopentanecarboxylate, HCl → Methyl 1-(5-bromo-1-oxoisoindolin-2-yl)cyclopentanecarboxylate

https://huagongshe.com/reaction/403963

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 1-amino-1-cyclopentanecarboxylate, HClHCID 11513856—
ReactantMethyl 4-bromo-2-(bromomethyl)benzoateHCID 22031079—
Reactant(R)-Methyl 2-(5-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 86673568—
ProductMethyl 1-(5-bromo-1-oxoisoindolin-2-yl)cyclopentanecarboxylateHCID 67313405—

Reaction Steps

The compound of example 368 was prepared analogous to compound of example 359 by reaction of the compound of example 358 and methyl 1-aminocyclopentanecarboxylate hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-72438040eda84a99b74ca38dfe17adf2
Source noteuspto-grants-2014_06