Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403969Generated: October 25, 2026

4-Aminobutyric acid methyl ester hydrochloride → Methyl 4-(5-bromo-1-oxoisoindolin-2-yl)butanoate

https://huagongshe.com/reaction/403969

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Aminobutyric acid methyl ester hydrochlorideHCID 2756383—
ReactantMethyl 4-bromo-2-(bromomethyl)benzoateHCID 22031079—
Reactant(R)-Methyl 2-(5-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 86673568—
ProductMethyl 4-(5-bromo-1-oxoisoindolin-2-yl)butanoateHCID 67306400—

Reaction Steps

The compound of example 374 was prepared analogous to compound of example 359 by reaction of the compound of example 358 and methyl 4-aminobutanoate hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-96c4f0921aab4edcba3bc6b0639d2c43
Source noteuspto-grants-2014_06