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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403972Generated: October 25, 2026

beta-Alanine, ethyl ester, hydrochloride → Ethyl 3-(5-bromo-1-oxoisoindolin-2-yl)propanoate

https://huagongshe.com/reaction/403972

Reaction equation

Participants

RoleNameHCIDCharge
Reactantbeta-Alanine, ethyl ester, hydrochlorideHCID 458475—
ReactantMethyl 4-bromo-2-(bromomethyl)benzoateHCID 22031079—
Reactant(R)-Methyl 2-(5-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 86673568—
ProductEthyl 3-(5-bromo-1-oxoisoindolin-2-yl)propanoateHCID 67307314—

Reaction Steps

The compound of example 377 was prepared analogous to compound of example 359 by reaction of the compound of example 358 and ethyl 3-aminopropanoate hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-387a3cef287a4767adf54ab62256bb55
Source noteuspto-grants-2014_06