HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-amino-2-phenylacetate hydrochloride → (S)-Methyl 2-(5-bromo-1-oxoisoindolin-2-yl)-3-phenylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-amino-2-phenylacetate hydrochloride | HCID 12247454 | — |
| Reactant | Methyl 4-bromo-2-(bromomethyl)benzoate | HCID 22031079 | — |
| Reactant | (R)-Methyl 2-(5-bromo-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 86673568 | — |
| Product | (S)-Methyl 2-(5-bromo-1-oxoisoindolin-2-yl)-3-phenylpropanoate | HCID 131731540 | — |
Reaction Steps
The compound of example 380 was prepared analogous to compound of example 359 by reaction of the compound of example 358 and 2-phenyl glycine methyl ester hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-25160e1f006f4b23973bca4b5a6caca9 |
| Source note | uspto-grants-2014_06 |