HRID403979

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID67308300

未命名化合物

HCID131731543

未命名化合物

PRODUCTS

产物

HCID67306385

未命名化合物

收率 89%

PROCEDURE

实验过程

The compound of example 385 was prepared analogous to the compound of example 361 by hydrolysis of the compound of example 384.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-71bf7668dbbd42ceb1b37d3093d15dd4
来源数据集: uspto-grants-2014_06
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US08748426B2
来源说明: uspto-grants-2014_06

反应SMILES

CC(C)[C@@H](N1CC2C(=CC=C(C3C=CC(NC(NC4C=CC=C(C(F)(F)F)C=4)=O)=CC=3)C=2)C1=O)C(O)=O.[CH3:38][O:39][CH2:40][C@H:41]([N:46]1[CH2:54][C:53]2[C:48](=[CH:49][CH:50]=[C:51]([C:55]3[CH:60]=[CH:59][C:58]([NH:61][C:62]([NH:64][C:65]4[CH:70]=[CH:69][CH:68]=[C:67]([C:71]([F:74])([F:73])[F:72])[CH:66]=4)=[O:63])=[CH:57][CH:56]=3)[CH:52]=2)[C:47]1=[O:75])[C:42]([O:44]C)=[O:43]>>[CH3:38][O:39][CH2:40][C@H:41]([N:46]1[CH2:54][C:53]2[C:48](=[CH:49][CH:50]=[C:51]([C:55]3[CH:56]=[CH:57][C:58]([NH:61][C:62]([NH:64][C:65]4[CH:70]=[CH:69][CH:68]=[C:67]([C:71]([F:74])([F:72])[F:73])[CH:66]=4)=[O:63])=[CH:59][CH:60]=3)[CH:52]=2)[C:47]1=[O:75])[C:42]([OH:44])=[O:43]