HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Methyl 2-(6-(5-(3-(4-chloro-2-phenoxyphenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate → (S)-2-(6-(5-(3-(4-Chloro-2-phenoxyphenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Methyl 2-(6-(5-(3-(4-chloro-2-phenoxyphenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 53302548 | — |
| Reactant | (S)-2-(6-(5-(3-(2-Chlorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 70975553 | — |
| Product | (S)-2-(6-(5-(3-(4-Chloro-2-phenoxyphenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 70975249 | 82% |
Reaction Steps
The compound of example 396 was prepared analogous to the compound of example 394 by hydrolysis of the compound of example 395.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-007275a49ff54bc2961216646294f620 |
| Source note | uspto-grants-2014_06 |