HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-Methyl 2-(6-(5-(3-(3,4-difluorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate → (S)-2-(6-(5-(3-(3,4-Difluorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-Methyl 2-(6-(5-(3-(3,4-difluorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoate | HCID 67323403 | — |
| Reactant | (S)-2-(6-(5-(3-(2-Chlorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 70975553 | — |
| Product | (S)-2-(6-(5-(3-(3,4-Difluorophenyl)ureido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 70975257 | 86% |
Reaction Steps
The compound of example 400 was prepared analogous to the compound of example 394 by hydrolysis of the compound of example 399.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-cc3fd201fbb54bf2b5a816dc5d11feaf |
| Source note | uspto-grants-2014_06 |