HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(6-(5-(4-tert-Butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid → (S)-3-Methyl-2-(1-oxo-6-(5-(4-pentylbenzamido)pyridin-2-yl)isoindolin-2-yl)butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(6-(5-(4-tert-Butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid | HCID 67306402 | — |
| Reactant | (S)-Methyl 3-methyl-2-(1-oxo-6-(5-(4-pentylbenzamido)pyridin-2-yl)isoindolin-2-yl)butanoate | HCID 131731553 | — |
| Product | (S)-3-Methyl-2-(1-oxo-6-(5-(4-pentylbenzamido)pyridin-2-yl)isoindolin-2-yl)butanoic acid | HCID 70975396 | 88% |
Reaction Steps
The compound of example 406 was prepared analogous to the compound of example 404 by hydrolysis of the compound of example 405.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-d9fe355f04cc46dfb3a6992e09a9d32a |
| Source note | uspto-grants-2014_06 |