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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 403997Generated: October 31, 2026

(S)-2-(6-(5-(4-tert-Butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acid → (S)-3-Methyl-2-(1-oxo-6-(5-(4-pentylbenzamido)pyridin-2-yl)isoindolin-2-yl)butanoic acid

https://huagongshe.com/reaction/403997

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(6-(5-(4-tert-Butylbenzamido)pyridin-2-yl)-1-oxoisoindolin-2-yl)-3-methyl butanoic acidHCID 67306402—
Reactant(S)-Methyl 3-methyl-2-(1-oxo-6-(5-(4-pentylbenzamido)pyridin-2-yl)isoindolin-2-yl)butanoateHCID 131731553—
Product(S)-3-Methyl-2-(1-oxo-6-(5-(4-pentylbenzamido)pyridin-2-yl)isoindolin-2-yl)butanoic acidHCID 7097539688%

Reaction Steps

The compound of example 406 was prepared analogous to the compound of example 404 by hydrolysis of the compound of example 405.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-d9fe355f04cc46dfb3a6992e09a9d32a
Source noteuspto-grants-2014_06