HCID 53302765, compound → HCID 67307586, compound

HRID 404030Notes

Reaction equation

HRID 404030 reaction equation
C(C1C=CC(NC(=O)NC2C=CC(C3C=C4C(CN([C@@H](C(C)C)C(O)=O)C4=O)=CC=3)=CC=2)=CC=1)#N.[C:36]([C:40]1[CH:72]=[CH:71][C:43]([C:44]([NH:46][C:47]2[N:52]=[CH:51][C:50]([C:53]3[CH:61]=[C:60]4[C:56]([CH2:57][N:58]([C@@H:63]([CH:68]([CH3:70])[CH3:69])[C:64]([O:66]C)=[O:65])[C:59]4=[O:62])=[CH:55][CH:54]=3)=[CH:49][CH:48]=2)=[O:45])=[CH:42][CH:41]=1)([CH3:39])([CH3:38])[CH3:37]>>[C:36]([C:40]1[CH:72]=[CH:71][C:43]([C:44]([NH:46][C:47]2[N:52]=[CH:51][C:50]([C:53]3[CH:61]=[C:60]4[C:56]([CH2:57][N:58]([C@@H:63]([CH:68]([CH3:69])[CH3:70])[C:64]([OH:66])=[O:65])[C:59]4=[O:62])=[CH:55][CH:54]=3)=[CH:49][CH:48]=2)=[O:45])=[CH:42][CH:41]=1)([CH3:38])([CH3:37])[CH3:39]

Participants

3

Reactant 2

HCID 53302765HCID 53302765, compoundHCID 67306310HCID 67306310, compound

Product 1

HCID 67307586HCID 67307586, compoundYield 88%

Procedure

The compound of example 492 was prepared analogous to the compound of example 40 by hydrolysis of the compound of example 491.

Sources & evidence

ORD record
ord-2eb5b5ebc4fb41e18873f1b19e9be24f
Source dataset
uspto-grants-2014_06
Patent number
US08748426B2

Reaction notes

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