HuagongsheHuagongshe Chemistry Print Report · For research reference only
(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → 2-Methyl-2-(1-oxo-6-(4-(4-(trifluoromethoxy)benzamido)phenyl)isoindolin-2-yl)propanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 53303631 | — |
| Reactant | Methyl 2-methyl-2-(1-oxo-6-(4-(4-(trifluoromethoxy)benzamido)phenyl)iso indolin-2-yl)propanoate | HCID 67307203 | — |
| Product | 2-Methyl-2-(1-oxo-6-(4-(4-(trifluoromethoxy)benzamido)phenyl)isoindolin-2-yl)propanoic acid | HCID 67306652 | 71% |
Reaction Steps
The compound of example 523 was prepared analogous to compound of example 98 by hydrolysis of compound of example 522.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-388d437ca7024b849fc4bd28b2fbc827 |
| Source note | uspto-grants-2014_06 |