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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404066Generated: October 26, 2026

Methyl 1-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclobutanecarboxylate → Methyl 1-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclobutanecarboxylate

https://huagongshe.com/reaction/404066

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 1-(6-(4-nitrophenyl)-1-oxoisoindolin-2-yl)cyclobutanecarboxylateHCID 67313692—
Reactant(S)-Methyl 2-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoateHCID 131731441—
ProductMethyl 1-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclobutanecarboxylateHCID 6731459171%

Reaction Steps

The compound of example 574 was prepared analogous to the compound of example 6 by reduction of the compound of example 573.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-69286b2d17094ca7b5f7fc464d2a0cef
Source noteuspto-grants-2014_06