HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 1-(1-oxo-6-(4-(4-(trifluoromethyl)benzamido)phenyl)isoindolin-2-yl)cyclobutanecarboxylate → 1-(1-Oxo-6-(4-(4-(trifluoromethyl)benzamido)phenyl)isoindolin-2-yl)cyclo butane carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 1-(1-oxo-6-(4-(4-(trifluoromethyl)benzamido)phenyl)isoindolin-2-yl)cyclobutanecarboxylate | HCID 53303003 | — |
| Reactant | (S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid | HCID 53303631 | — |
| Product | 1-(1-Oxo-6-(4-(4-(trifluoromethyl)benzamido)phenyl)isoindolin-2-yl)cyclo butane carboxylic acid | HCID 67307889 | 96% |
Reaction Steps
The compound of example 580 was prepared analogous to compound of example 98 by hydrolysis of compound of example 579.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748426B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-9abd8b42543c4f0087c1d97bf34316e0 |
| Source note | uspto-grants-2014_06 |