4-Methylbenzoyl Chloride → Methyl 1-(6-(4-(4-methylbenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclobutane carboxylate

Participants

Role	Name	HCID	Charge
Reactant	4-Methylbenzoyl Chloride	HCID 13405	—
Reactant	Methyl 1-(6-(4-aminophenyl)-1-oxoisoindolin-2-yl)cyclobutanecarboxylate	HCID 67314591	—
Reactant	(S)-Methyl 2-(6-(4-benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoate	HCID 123625862	—
Product	Methyl 1-(6-(4-(4-methylbenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclobutane carboxylate	HCID 67307652	96%

The compound of example 581 was prepared analogous to compound of example 97 by reaction of compound of example 574 with 4-methyl benzoyl chloride.