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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 404072Generated: October 26, 2026

(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acid → 1-(6-(4-(4-Methylbenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclobutane carboxylic acid

https://huagongshe.com/reaction/404072

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(S)-2-(6-(4-Benzamidophenyl)-1-oxoisoindolin-2-yl)-3-methylbutanoic acidHCID 53303631—
ReactantMethyl 1-(6-(4-(4-methylbenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclobutane carboxylateHCID 67307652—
Product1-(6-(4-(4-Methylbenzamido)phenyl)-1-oxoisoindolin-2-yl)cyclobutane carboxylic acidHCID 6730683087%

Reaction Steps

The compound of example 582 was prepared analogous to compound of example 98 by hydrolysis of compound of example 581.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08748426B2
Source datasetuspto-grants-2014_06
ORD IDord-95f731c1ee3b4107b3ffe240d74db8f0
Source noteuspto-grants-2014_06